

🐾 Stay ahead of pests with FRONTLINE Plus — because your big dog deserves big protection!
FRONTLINE Plus Flea and Tick Treatment offers fast-acting, waterproof protection for extra-large dogs weighing 89 to 132 lbs. This trusted topical solution kills fleas, flea eggs, larvae, chewing lice, and ticks that can transmit Lyme disease, providing continuous defense for 30 days with just one monthly application. Proven effective for over 20 years, it breaks the flea life cycle and is easy to apply, making it the go-to choice for pet owners committed to year-round parasite control.

















| ASIN | B0002J1FP8 |
| ASIN | B0002J1FP8 |
| Age Range Description | All Life Stages |
| Best Sellers Rank | #2,491 in Pet Supplies ( See Top 100 in Pet Supplies ) #12 in Dog Flea Drops |
| Brand Name | Frontline |
| Breed Recommendation | Large Breeds |
| Color | Red Box |
| Country of Origin | France |
| Customer Reviews | 4.4 4.4 out of 5 stars (15,131) |
| Date First Available | May 30, 2004 |
| Date First Available | May 30, 2004 |
| Department | Flea & Tick |
| Department | Flea & Tick |
| Directions | Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze… |
| Included Components | Package includes 3 applicators |
| Is Discontinued By Manufacturer | No |
| Item Dimensions LxWxH | 5.75 x 0.75 x 4.5 inches |
| Item Package Dimensions L x W x H | 5.87 x 4.37 x 0.75 inches |
| Item Weight | 1.6 Ounces |
| Item model number | 72220 |
| Item model number | 72220 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer recommended age | 1 month and up |
| Model Name | FRONTLINE Plus Extra Large Dog |
| Number of Items | 3 |
| Product Dimensions | 5.75 x 0.75 x 4.5 inches; 1.6 ounces |
| Size | 3 Count |
| Specific Uses for Product | Parasites |
| Style | 3 Count |
| Target Audience Keyword | dogs |
| Warranty Description | If you are not satisfied with FRONTLINE Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842 |
T**E
This stuff still works great
I bought this because I remember, this was the first thing that came out to kill fleas & ticks! I haven't seen any in years! I'm glad I found it on Amazon! Because I can't afford the other stuff & too! The other stuff I don't really trust it much! This is well worth the money, & has worked great on my 116 pound German shepherd, yup she could lose a few pounds. But she's not scratched for fleas.. she does have dry skin. There was no smell & always fell safe applying the tube opening it away from me & applying it between the shoulder's! So thankful they still make Frontline & it works! Am definitely going to be buying more!
S**H
Still works in my part of the state
Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away...
S**.
Medicine
It help to keep the ticks and flees away from the dogs
K**R
Flea med
Helps but bad year and not lasting for maybe 2weeks at most on the dogs
K**J
Best flea and tick med!
Arrived quickly. Always works so well for fleas and ticks for our 2 German Shepherds (very thick hair). We live on lots of land with woods so they come into contact with fleas/ticks, but when Frontline is used, we don’t have any problems. Love the bigger pack that is offered and at the best price!! Fleas: No fleas on our dogs! Ease of application: Just takes a few seconds to apply!
J**K
A must have for my dogs
I have been using Frontline for years and will continue to do so. The ease of application and the protection it provides has been favored by me and my dogs. I usually by a 3 month supply for each of my dogs. It is becomes clear if I forget to give it my dogs. In my opinion each dose does last almost exactly one month. Usually I will notice the dogs starting to scratch if I forget. As soon as I apply, by the end of the day, the scratching will stop. I love knowing my dogs are protected. I have a lot of stray cats that invade my yard and they always carry fleas so knowing my dogs get what they need to reduce the fleas is essential. To apply, I break of the top of each little vial and apply directly on the skin above their shoulders. The dogs dont even notice. It is very easy. My dogs don't like taking anything in a pill form and just spit them out, so having this where I apply topical is better for me. I highly recommend. This product works and I don't think you will be disappointed. I will add to make sure you use the right product which is determined by the weight of your pet. I don't know, nor do I want to find out if I give my 70lb dog the same product as my 120lb. Just buy the one that is designed for the weight of your dog. Other than that, I highly recommend.
A**Y
Good product
Product works well, I live in Florida, off grid, in the woods. We have lots of sand, and my lab is active and always playing in the forest. I never have problems with ticks or fleas. Nats are still a pain, but I use Avons, Skin So Soft, I spray it on my hands, lightly pass over her eyes, back and tail. I've never seen skin or eye irritation from any of my dogs. From the flea control or the Skin so soft. Hope this helps.
5**0
WASTE OF MONEY DOESN'T WORK!!!!
Since application I have literally pulled off seven ticks. Some attached some crawling to attach. Literally pulled two off within 6 hours of application. The rest have been within the last week. We have Lyme disease here. This was the reason why I got this. If my dog ends up with Lyme disease you'll end up with a bill!! I want my money back. Don't listen to their money back. Guarantee you call that number on the back of the box and they just want to find all sorts of loopholes of reasons. Why not to give you your money back. They want ticks to eat on your dog up to 3 months! It doesn't matter where I purchased it. The facts are the facts. It does not work! seven ticks 3 weeks. Says "kills ticks including those that may transmit Lyme disease" when you talk to the company they say it doesn't protect against Lyme disease! Fair the definition of what's wrong with companies finding loopholes to basically screw over their customers.
Z**E
It says there is 6 doses inside but i received only 3 and package was opened!
Trustpilot
2 weeks ago
1 week ago