NuMedica NeuroMethylation Cream Foundation Formula Description Advanced Neuro-Immune Support Gluten Free NeuroMethylation Cream™ contains five essential nutrients that support the methylation processes associated with neurological and immune system function.* Neuro Methylation Cream™ is the foundation formula in NuMedica’s Advanced Neuro-Immune Program. This topical cream supports immune health and normal neurotransmitter production and metabolism.* The 5-MTHF in this formula is also known as the "L" form of 5-MTHF since it is the reduced form of folate. Directions Recomended Application (for external use only):Maintenance Application: 2 pumps daily (1 pump in the morning and 1 pump 2 hours prior to bedtime) on a hairless area or as directed by your healthcare practitioner. For children, the best area for application is on the back. Advanced Application: 3 pumps daily (1 pump in the morning, 1 pump at midday, 1 pump 2 hours prior to bedtime). Disclaimer These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.