---
product_id: 361203782
title: "S3 PYO Shampoo 16.9 oz (500 mL)"
brand: "douxo"
price: "S$119"
currency: SGD
in_stock: true
url: https://www.desertcart.sg/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml
store_origin: SG
region: Singapore
---

# Hypoallergenic formula Ophytrium ingredient 500 mL volume S3 PYO Shampoo 16.9 oz (500 mL)

**Brand:** douxo
**Price:** S$119
**Availability:** ✅ In Stock

## Summary

> 🐶 Pamper Your Pets with the Best!

## Quick Answers

- **What is this?** S3 PYO Shampoo 16.9 oz (500 mL) by douxo
- **How much does it cost?** S$119 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sg](https://www.desertcart.sg/products/361203782-s3-pyo-shampoo-16-9-oz-500-ml)

## Best For

- douxo enthusiasts

## Why This Product

- Trusted douxo brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Rapid Results:** See a reduction in yeast counts in just 7 days!
- • **Perfect Pairing:** For optimal results, combine with DOUXO PYO Mousse.
- • **Gentle & Effective:** Free from soaps, sulfates, and parabens for a soothing cleanse.
- • **Supports Skin Health:** Hydrates and strengthens the skin's natural barrier.
- • **Veterinarian Recommended:** The #1 non-prescription brand trusted by U.S. vets for your furry friends.

## Overview

Douxo S3 PYO Shampoo is a veterinarian-recommended, hypoallergenic shampoo designed for dogs and cats. This 500 mL formula features ophytrium, a natural ingredient that supports skin health, hydrates, and helps reduce yeast counts in just 7 days. Free from harmful additives, it’s the perfect choice for pet owners seeking effective and gentle grooming solutions.

## Description

Douxo S3 PYO Shampoo 16.9 oz (500 mL)

## Features

- #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with infections/inflammatory dermatological disease
- Proven to disinfect, hydrate and help support the skin's ecosystem and reduce yeast counts in 7 days
- Contains ophytrium, a purified natural ingredient that helps support the skin’s physical barrier for supple hydrated skin and helps soothe irritated skin
- Free from soaps, sulfates, parabens, dyes and nanoparticles
- For best results use with the DOUXO PYO Mousse

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Liquid volume | 500 Milliliters |
| Special ingredients | ophytrium |
| Target species | Dogs and Cats |
| Allergen information | Hypoallergenic |
| UPC | 850002593433 |
| Manufacturer | Douxo S3 |
| Department | Grooming |
| Item model number | D98420E |
| Package Dimensions | 19.1 x 8.66 x 5.11 cm; 479.11 g |
| ASIN | B0949RKDYC |

## Product Details

- **Brand:** DOUXO
- **Scent:** Unscented
- **Product benefits:** Disinfectant, moisturizing and supporting the skin ecosystem, reducing yeast count in 7 days
- **Recommended uses for product:** Irritated Skin,Moisturizing
- **Item form:** Mousse

## Images

![S3 PYO Shampoo 16.9 oz (500 mL) - Image 1](https://m.media-amazon.com/images/I/61jtHvPDqfL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: What happened to the original formula that had these active ingredients: chlorhexadine 3%, climbazole .5%, phytosphingosine salicyloyl .05%??????**
A: I talked to my Dog's Allergy Vet's office recently about this. They told me they reformulated this and took out some ingredients due to some Dog's having a reaction to it. Also, I don't like it and its nothing like the original formula. It doesn't suds up and I had to use more than double the amount the directions said on my 8 lb dog.

**Q: I'm using the other brand of Douxo for my dog's skin allergies. How does this compare to the other Douxo?**
A: This product is specifically designed to relieve bacterial or fungal skin infections. Specifically, it helps to soothe irritated skin. If your dog has skin allergies, this particular shampoo could be a good choice since it is the #1 non-prescription topical brand used and recommended by U.S. veterinarians.

**Q: Why doesn't it say antifungal any more? it still says it in the description but no longer on the bottle? why?**
A: Mine says antifungal anticeptic

**Q: Who can i message that sells this product?**
A: We do :)

## Frequently Bought Together

- Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 16.9 fl. oz. (500mL)
- Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)
- Douxo S3 Pyo Pads, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 30 Pads

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*Product available on Desertcart Singapore*
*Store origin: SG*
*Last updated: 2026-02-12*