---
product_id: 228744810
title: "Globe Extra Strength Anti Itch Cream,Histamine Blocker, 4 Pack, 1.5 oz | Diphenhydramine Formula, Zinc Acetate, Outdoor Itch Care, Skin Comfort Cream, Compact Tubes, First Aid Supply"
brand: "globe"
price: "S$27"
currency: SGD
in_stock: true
reviews_count: 8
category: "Globe"
url: https://www.desertcart.sg/products/228744810-globe-extra-strength-anti-itch-cream-histamine-blocker-4-pack
store_origin: SG
region: Singapore
---

# 2% Diphenhydramine HCl for rapid itch relief Fast-acting formula for poison ivy & insect bites 0.1% Zinc Acetate skin protectant barrier Globe Extra Strength Anti Itch Cream,Histamine Blocker, 4 Pack, 1.5 oz | Diphenhydramine Formula, Zinc Acetate, Outdoor Itch Care, Skin Comfort Cream, Compact Tubes, First Aid Supply

**Brand:** globe
**Price:** S$27
**Availability:** ✅ In Stock

## Summary

> 🛡️ Stop the itch, start the day—relief that keeps up with your hustle!

## Quick Answers

- **What is this?** Globe Extra Strength Anti Itch Cream,Histamine Blocker, 4 Pack, 1.5 oz | Diphenhydramine Formula, Zinc Acetate, Outdoor Itch Care, Skin Comfort Cream, Compact Tubes, First Aid Supply by globe
- **How much does it cost?** S$27 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sg](https://www.desertcart.sg/products/228744810-globe-extra-strength-anti-itch-cream-histamine-blocker-4-pack)

## Best For

- globe enthusiasts

## Why This Product

- Trusted globe brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Skin Shield Technology:** 0.1% zinc acetate protects and soothes irritated skin, accelerating healing.
- • **Instant Comfort, Anytime:** Fast-acting formula delivers immediate itch and pain relief to keep you moving.
- • **Multi-Use Outdoor Savior:** Effective on insect bites, poison ivy, minor burns, and sunburns—your all-in-one relief.
- • **Power-Packed Itch Defense:** Clinically proven 2% diphenhydramine HCl stops itching fast so you never miss a moment.
- • **Trusted Quality Assurance:** Made in the USA under strict pharmaceutical standards with NDC certification for peace of mind.

## Overview

Globe Extra Strength Itch Stopping Cream is a fast-acting, clinically formulated topical analgesic containing 2% diphenhydramine HCl and 0.1% zinc acetate. Designed to relieve itching and pain from insect bites, poison ivy, minor burns, and skin irritations, this 4-pack offers reliable, pharmaceutical-grade protection and soothing care for all skin types.

## Description

Buy (4 Pack) Globe Extra Strength Itch Stopping Anti-Itch Cream 1.5 Oz with Histamine Blocker, Diphenhydramine HCl Topical Analgesic & Zinc Acetate Skin Protectant for Relief from Most Outdoor Itches on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Stops the itch! - Yay! 5 stars! I used on an allergic reaction dermatitis and instant relief from pain and itch. Also very reasonably priced
Review: Anti-itch cream works well for dry skin - Every once in a while I will get a dry itchy patch, seemingly always near an elastic band in my clothes. This cream has helped immensely when I need itch relief. Good quality. No smell, and a very nice price keep me coming back for more: Recommend.

## Features

- EXTRA STRENGTH ITCH RELIEF: Get extra strength itch relief from Globe with this antihistamine cream that also protects your skin.
- EFFECTIVE AND PROVEN FORMULA: Compare to the Leading expensive Name Brand. Formula contains 2% diphenhydramine HCL, a topical analgesic pain reliever and 0.1% zinc acetate skin protectant.
- FAST, RELIEF FROM PAIN AND ITCH: Globe Stop Itching Cream relieves pain and itching associated with insect bites, minor burns, sunburn, minor skin irritations and cuts.
- POISON IVY TREATMENT: Globe Stop Itching Cream relieves pain and itching associated with poison ivy, poison oak, and sumac. Dries the oozing and weeping of Poison ivy, oak, and sumac.
- IMMEDIATE RELIEF: Receive immediate relief from itching. Contains strong active ingredients that allow you to keep on with your day without that annoying itch.
- QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. Trifecta Pharmaceuticals USA, who manufacturers the Globe Brand and is based in sunny Fort Lauderdale, Florida.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B08B43XTGY |
| Active Ingredients | Diphenhydramine hydrochloride , Zinc acetate |
| Additional Features | Fast-Acting |
| Age Range Description | All |
| Best Sellers Rank | #32,872 in Health & Household ( See Top 100 in Health & Household ) #54 in Insect Bite Treatments |
| Brand | Globe |
| Brand Name | Globe |
| Container Type | Bottle |
| Customer Reviews | 4.6 out of 5 stars 316 Reviews |
| Dosage Form | Cream |
| Flavor | Original |
| Included Components | Diphenhydramine hydrochloride , Zinc acetate |
| Item Dimensions | 7 x 1 x 5 inches |
| Item Form | Cream |
| Item Nype Name | Itch Stopping Cream Compare to Benadryl |
| Item Weight | 6 Ounces |
| Item dimensions L x W x H | 7 x 1 x 5 inches |
| Manufacturer | Trifecta Pharmaceuticals USA |
| Manufacturer Part Number | 4953-FBA22 |
| Model Number | 4953-FBA22 |
| Number of Items | 4 |
| Package Type Name | Tube |
| Product Benefits | Itch Control |
| Specific Uses For Product | Anti Itch |
| Target Use Body Part | Whole Body |
| UPC | 860003665770 |
| Unit Count | 6.0 Ounce |

## Product Details

- **Brand:** Globe
- **Special Feature:** Fast-Acting
- **Item Weight:** 6 Ounces
- **Item dimensions L x W x H:** 7 x 1 x 5 inches
- **Product Benefits:** Itch Control

## Images

![Globe Extra Strength Anti Itch Cream,Histamine Blocker, 4 Pack, 1.5 oz | Diphenhydramine Formula, Zinc Acetate, Outdoor Itch Care, Skin Comfort Cream, Compact Tubes, First Aid Supply - Image 1](https://m.media-amazon.com/images/I/71yFvIlCZ+L.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Stops the itch!
*by D***R on April 30, 2026*

Yay! 5 stars! I used on an allergic reaction dermatitis and instant relief from pain and itch. Also very reasonably priced

### ⭐⭐⭐⭐⭐ Anti-itch cream works well for dry skin
*by A***R on April 30, 2024*

Every once in a while I will get a dry itchy patch, seemingly always near an elastic band in my clothes. This cream has helped immensely when I need itch relief. Good quality. No smell, and a very nice price keep me coming back for more: Recommend.

### ⭐⭐⭐⭐⭐ Works as intended, just as the name brand stuff but a portion of the cost
*by C***R on July 24, 2025*

Works great! Same medications as the expensive versions and works just as good! Great value. Would buy again

## Frequently Bought Together

- (4 Pack) Globe Extra Strength Itch Stopping Anti-Itch Cream 1.5 Oz with Histamine Blocker, Diphenhydramine HCl Topical Analgesic & Zinc Acetate Skin Protectant for Relief from Most Outdoor Itches
- Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube
- MED Pride Hydrocortisone 1 Percent Cream Anti Itch for Redness, Swelling, Rash, Bug Bites, Eczema Bulk Pack of 4 Travel Size 1 Oz Tubes

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.sg/products/228744810-globe-extra-strength-anti-itch-cream-histamine-blocker-4-pack](https://www.desertcart.sg/products/228744810-globe-extra-strength-anti-itch-cream-histamine-blocker-4-pack)

---

*Product available on Desertcart Singapore*
*Store origin: SG*
*Last updated: 2026-07-27*