Is this size enought to handle three separate drains?

Nope. You should use the entire bottle for each drain

is this for plastic pipes?

A word of caution: Products such as Liquid Plumr and Drano are strong enough to break up clogs in your pipes such as hair, food or grease, and they do work in some instances, but you should use caution when pouring them down the drain. Liquid Plumr and Drano are chemically designed to eat away at whatever is clogging your pipes, which can result in damaging plastic or even metal pipes. https://www.superiordrain.com/are-liquid-drain-cleaners-harmful-to-pipes.

Is it necessary to wear a mask when using?

I had no reason to wear a mask - I am sensitive to smells and this was fine - of course, I didn't stick my head down in the sink! Just squirted it in the drain - and followed the directions. its a good product!

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🚿 Clear drains, clear mind — don’t let clogs cramp your style!

HAIR CLOG SPECIALIST - Formulated specifically to dissolve stubborn hair blockages with ease.
QUICK ACTION FORMULA - Experience rapid clog removal and get back to your day with zero downtime.
GENEROUS 96 OZ VOLUME - Enough solution to handle multiple drains or heavy-duty clogs without running out.
TRUSTED BRAND RELIABILITY - Liquid-Plumr’s proven formula keeps your pipes flowing smoothly and worry-free.
UNMATCHED PRO STRENGTH POWER - Tackles the toughest clogs fast, so you never miss a beat.

Liquid-Plumr Pro-Strength Clog Remover is a 96 fluid ounce drain opener designed to quickly dissolve hair clogs and tough blockages. Its specialized formula ensures efficient, professional-grade performance, making it an essential tool for maintaining free-flowing drains in any busy household.