

🧴 Unlock the secret to calm, itch-free skin—because your hands deserve the best!
E45 Dermatological Itch Relief Cream is a clinically formulated, fast-absorbing cream designed to soothe and relieve skin irritation and eczema. Packaged hygienically in a large 500g container, it boasts a 4.6-star rating from nearly 3,000 users, making it a trusted choice for effective, long-lasting skin comfort.
| ASIN | B001EJOHUU |
| ASIN | B001EJOHUU |
| Best Sellers Rank | #187,764 in Beauty ( See Top 100 in Beauty ) #2,709 in Body Creams |
| Customer reviews | 4.6 4.6 out of 5 stars (2,983) |
| Date First Available | 9 August 2012 |
| Is Discontinued By Manufacturer | No |
| Item model number | 348713 |
| Item model number | 348713 |
| Product Dimensions | 5 x 5 x 24 cm; 550 g |
| Product Dimensions | 5 x 5 x 24 cm; 550 g |
U**4
Cream is fast absorbent which helps relieve skin irritation. Recommended
W**S
HEAVEN in a bottle 🙌🏽🙌🏽🙌🏽🙌🏽 I have been suffering with eczema on both of my hands, of all places since June 2025 and I have literally tried EVERYTHING.. nothing works. Not even the prescribed medication. Long story short I read a post about E45 on Facebook about the same condition I have. Extreme itching, eczema. Yada Yada.. it hasn’t even been 24 hours. I could cry 😭 I know it’s pricey but it’s worth it!
B**B
Very happy, it can also be used as a general moisturiser, its smooth and "creamy" (Wouldn't want to eat it though) it is absorbed quickly into the skin
H**A
Bought this for my father in law bc he was itching like crazy!! I think he has excema but won't go get it checked out. He would itch until the point of bleeding. So a friend told me about this cream that helped her. I ordered it and low and behold it worked! He loves it so much the bottle is almost empty and I got it like 6 months ago. It was very effective for him and he stopped itching when he put it on. Will be buying again for him and also no more bleeding thank god!
G**A
This is a life saver I have very itchy upper arms since my stroke non greasy & pump easy to use I’d recommend it every time